SAN FRANCISCO, CA — September 15, 2026 (STL.News) The death of a 16-year-old San Francisco teenager has brought new attention to cychlorphine, an emerging synthetic opioid more potent than fentanyl that has rapidly appeared in fatal overdoses, counterfeit pharmaceutical pills and illicit drug supplies across the United States and internationally. Four people were arrested in San Francisco following a months-long investigation that began after the teenager’s fatal April overdose, San Francisco police announced Monday. But a deeper review by STL.News of federal, international and forensic toxicology reports shows that the threat extends far beyond California. Cychlorphine — also known
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